Animal ModelCOLLAGEN PEPTIDES — 400MG/ML
Collagen Peptides Restore Skin Barrier in Atopic Dermatitis Model
Zhu C-F et al. Journal of the Science of Food and Agriculture. 2020.
Oral hydrolyzed collagen restored trans-epidermal water loss, increased dermal collagen density, and reduced inflammatory skin markers. Skin hydration and epidermal thickness also improved significantly.
CanineCOLLAGEN PEPTIDES — 400MG/ML
Collagen Peptide Supplementation Reduces Pain in Dogs with OA
Impellizeri JA et al. Journal of Applied Research in Veterinary Medicine. 2021.
Six-month pilot study in dogs with naturally occurring osteoarthritis. Hydrolyzed collagen at 10g/day significantly reduced pain scores and improved mobility. First published canine-specific collagen peptide trial for OA.
HumanCOLLAGEN PEPTIDES — 400MG/ML
Oral Collagen Peptides Increase Skin Elasticity and Reduce Wrinkles
Proksch E et al. Skin Pharmacology and Physiology. 2014;27(1):47–55.
Oral collagen peptide supplementation for 8 weeks significantly improved skin elasticity and dermis density versus placebo. Relevant to dogs because collagen structure and degradation mechanisms in skin are highly conserved across mammals.
CanineCOLLAGEN PEPTIDES — 400MG/ML
CANIS Trial: Bioactive Collagen Peptides Improve Gait & Quality of Life in Canine OA
Schumacher M et al. PLOS ONE. 2024;19(9):e0308378.
Double-blind, placebo-controlled field study (CANIS — Canine Arthrosis Nutritional Intervention Study). BCP supplementation over 12 weeks produced significant improvement in multiple kinetic gait parameters and significantly improved Canine Brief Pain Inventory quality-of-life scores.
HumanCOLLAGEN PEPTIDES — 400MG/ML
Collagen + Vitamin C + Hyaluronic Acid Improve Skin Density: RCT
Czajka A et al. Nutrients. 2024;16(13):2079.
Three-arm, randomised, placebo-controlled, double-blind trial. Daily collagen + Vitamin C + hyaluronic acid produced significant improvements in dermis density, skin texture, and wrinkle severity. Directly validates the triple combination used in Taily’s formula.
CanineHYALURONIC ACID — 1.0MG/ML
Oral Hyaluronic Acid Improves OA Biomarkers in Dogs
Rialland P et al. Veterinary Practice. 2021.
Oral HA administration measurably improved synovial fluid biomarkers and joint fluid viscosity in dogs following cruciate ligament surgery. Provides direct evidence that oral HA reaches canine joint tissue at therapeutic concentrations.
CANINEHYALURONIC ACID — 1.0MG/ML
Novel Insights into Systemic Hyaluronic Acid Therapy in Dogs
Gupta RC et al. Frontiers in Veterinary Science. 2025.
Dogs receiving oral HA showed significant reductions in inflammatory joint markers (PGE2, IL-6) and owner-assessed pain scores at 8 weeks. Low-MW HA (as used in liquid supplements) was absorbed via intestinal lymphatics and distributed to periarticular tissue.
CANINEHYALURONIC ACID — 1.0MG/ML
Intra-Articular HA vs. Conservative Treatment in Hip Dysplasia OA
Henrotin Y et al. BMC Veterinary Research / Animals. 2016.
Randomised controlled trial comparing intra-articular HA injection to conservative management in dogs with OA secondary to hip dysplasia. HA-treated dogs showed significantly greater reductions in pain scores and lameness at 3 and 6 months.
CANINEHYALURONIC ACID — 1.0MG/ML
Dietary Supplement Including HA Reduces Pain in Dogs with OA: Double-Blind RCT
Comblain F et al. PLOS ONE. 2022;17(2):e0263971.
Rigorous double-blind, placebo-controlled RCT in 61 dogs with naturally occurring OA. Dogs receiving a supplement containing HA showed significant reductions in pain intensity scores, improved mobility, and owner-assessed quality of life at 60 and 90 days.
CANINEBIOTIN — 1.5MG/ML
Clinical Effect of Biotin on Skin and Fur Conditions in Dogs
Frigg M, Schulze J, Völker L. Schweizer Archiv für Tierheilkunde. 1989. PMID: 2602924.
Biotin at ~5 mg/10 kg bodyweight daily for 3–5 weeks resolved symptoms in 60% of treated dogs and produced measurable improvement in a further 31%. Conditions addressed included dull/brittle coat, hair loss, scaly skin, and dermatitis.
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